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Nonilex

A tiny French village became an hot spot. Neurologists found that the patients consistently ate three foods: game, dandelion greens, and, notably, wild mushrooms. @shayla__love traveled there to investigate:

An ‘Impossible’ Outbreak in the

In one tiny town, more than a dozen people were diagnosed with the rare neurodegenerative disease ALS.

By Shayla Love
Photographs by Elliott Verdier

theatlantic.com/health/archive

The Atlantic · Was a Mushroom Behind an ALS Outbreak in the Alps?By Shayla Love
Mar 23, 2025, 01:52 PM·Public·Mastodon for iOS
23boosts·16favorites
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Darren

@Nonilex thanks ! that’s quite sobering. regular reminder that life has been trying to kill us unsuccessfully for 2 billion years. someone should try deep sequencing some samples to see what the mutation pattern is. They might be able to tie it back to mechanism. Reminiscent of Balkan kidney damage due to consumption of aristocholic acid (birthwort).

pubmed.ncbi.nlm.nih.gov/174349

PubMedAristolochic acid mutagenesis: molecular clues to the aetiology of Balkan endemic nephropathy-associated urothelial cancer - PubMedBalkan endemic nephropathy (BEN) is found in certain rural areas of the Balkans and affects at least 25,000 inhabitants. Of the many hypotheses on BEN, the Aristolochia hypothesis has recently gained ground substantiated by the investigations on aristolochic acid nephropathy (AAN). On both clinical …
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