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#medicine

184 posts129 participants8 posts today
Public
MottG

I have started a new weekly newsletter that will be a bibliography of new research articles on the use of automated knowledge discovery in medicine. The bibliography is compiled by a machine learning program developed by Thomas Kirchel, to which I provide manual abstract relevance feedback. You can subscribe to it free by signing up for the newsletter "bims-aukdim Automated knowledge discovery techniques in medicine" at:

biomed.news/reports

Screenshot of part of the first issue of bims-aukdim newsletter on "Automated knowledge discovery techniques in medicine" showing a list of 16 research papers followed by abstracts of each one.
#research#medicine#knowledgeDiscovery
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Brittany Trang

The lab's efforts aren't duplicated anywhere, there's no $ to be made so the private sector won't step in, and this lab is key to fighting anti-microbial resistance.

“To me, this is like a blind man with a chainsaw has just gone through the system and arbitrarily cut things without any rationale.”

statnews.com/2025/04/05/cdc-se

STAT · CDC’s top laboratory on sexually transmitted diseases is shut by Trump administrationThe Trump administration fired everyone in a CDC lab that is crucial to tracking drug-resistant gonorrhea and other sexually transmitted diseases. "We are blind," an expert says.
#health#healthcare#publichealth
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Joseph Meyer

A Trend I May Not Like

A few years ago, a very good primary care physician who I had been seeing for decades joined a national chain of medical providers called Village Medical. I have not noticed a drop off in the quality of services. But, there is a less personal feel than what I experienced with private practitioners for most of my life and I am a bit worried about the more distant future of medicine.

This morning, I received an email announcing my dentist is making the same move, joining a national group called High Point Dentistry. The email is written to reassure me: “So what’s changing? Just the name. We’re gaining added support, resources, and dental specialists that will allow us to enhance your experience.” The online ratings of other branches around the country are great. But, I don’t entirely trust online ratings.

Does this amount to a growing capitalist takeover of medicine by the U.S. corporate world? Will the future be more like “trickle down” medicine? Is less administrative work, reduced malpractice risk, or something else the incentive for physicians to join these chains rather than remaining independent? Even if the medical services are okay for now, I worry that may not remain the case after big business has captured a sizable majority of practices and decides to focus more on profit and less on patient care.

#Medicine#Physicians#Doctors
Public
Global News Ottawa

Canadian scientist wins Breakthrough Prize for discovery of hormone used in Ozempic, Mounjaro
A Canadian scientist has won a 2025 Breakthrough Prize in Life Sciences for discovering a hormone used in diabetes and obesity medications that has changed the lives of millions.
#science #medicine #award #Health #BreakthroughPrize #DrDanielDrucker
globalnews.ca/news/11117783/ca

Public
Global News

Canadian scientist wins Breakthrough Prize for discovery of hormone used in Ozempic, Mounjaro
A Canadian scientist has won a 2025 Breakthrough Prize in Life Sciences for discovering a hormone used in diabetes and obesity medications that has changed the lives of millions.
#science #medicine #award #Health #BreakthroughPrize #DrDanielDrucker
globalnews.ca/news/11117783/ca

Public
Global News Peterborough

Canadian scientist wins Breakthrough Prize for discovery of hormone used in Ozempic, Mounjaro
A Canadian scientist has won a 2025 Breakthrough Prize in Life Sciences for discovering a hormone used in diabetes and obesity medications that has changed the lives of millions.
#science #medicine #award #Health #BreakthroughPrize #DrDanielDrucker
globalnews.ca/news/11117783/ca

Public
Global News Hamilton

Canadian scientist wins Breakthrough Prize for discovery of hormone used in Ozempic, Mounjaro
A Canadian scientist has won a 2025 Breakthrough Prize in Life Sciences for discovering a hormone used in diabetes and obesity medications that has changed the lives of millions.
#science #medicine #award #Health #BreakthroughPrize #DrDanielDrucker
globalnews.ca/news/11117783/ca

Public
Frankie ✅

The American Plan to Eliminate Vaccines | Office for Science and Society

mcgill.ca/oss/article/medical-

Office for Science and SocietyThe American Plan to Eliminate VaccinesWe don’t defend the things we take for granted. Vaccines have long been victims of their own success, but only insofar as too many people were hesitant to get them. But what if vaccines were eliminated altogether? It’s hard to ring the alarm these days without sounding mad. The eradication of vaccines from the United States? It may seem farfetched to people who don’t pay attention to the Trump administration’s actions vis-à-vis public health, but the recent announcement that David Geier is to be a senior data analyst on a study of vaccines and autism commissioned by the American federal government is one more step toward eliminating one of humanity’s scientific triumphs. Vaccines do not cause autism. I have recently written about how we know that vaccines are safe. You can also spend a day reading the many, many credible papers answering this question. The debate has been put to rest by the scientific community and is being kept on life support by activists who deny the consensus on this issue. They will often prop up bad studies birthed by anti-vaxxers. The problem for their credibility is that these studies do not emanate from the government of the most powerful country on Earth. This is about to change. Dumpster diving at the CDC You would expect an organization called the Institute of Chronic Diseases to occupy a large glass building on a university campus, filled with people dressed in white lab coats. But the nonprofit’s yearly tax filings since 2013 show one name running the show: Dr. Mark Geier. Under “Compensation of five highest-paid employees,” we read a single word: NONE. The self-described institute was led by Dr. Mark Geier, who according to RFK Jr’s anti-vaccine organization, Children’s Health Defense, passed away a few weeks ago. On paper, he looked like a legitimate physician-researcher: a bachelor’s degree in zoology, a doctorate in genetics, and a medical degree, all from George Washington University in D.C. His obituary on the site lists various affiliations as diplomat and co-founder of a few scientific and medical endeavours, and it notes that he is survived by “his son and tennis partner,” David. While his father’s credentials are impressive, David’s are much shorter (and he should not be confused with Dr. David Geier, an orthopaedic surgeon). He has neither doctorate nor medical degree, but a bachelor’s of arts in biology and a few graduate-level classes. Why would David Geier be recruited by the Department of Health and Human Services to conduct a study on whether or not vaccines cause autism? Because Kennedy is not driven by curiosity but by his preexisting belief that vaccines are responsible for autism. Pseudoscience is often steered by confirmation bias, where the conclusion comes first and the evidence must follow, otherwise it is rejected. Cherry-picking allows for small, skewed studies to be heralded as definitive proofs, while larger, rigorous trials are dismissed as coming from corrupt sources. David Geier was chosen because he will deliver the conclusion Kennedy already believes in. Mark and David Geier have a long history of unethical research practices, the most amusing example of which may be the 2017 retraction of a paper they co-authored and which argued that conflicts of interest may explain why most studies on the vaccine-autism link failed to find an association. The twist? On top of a number of errors, the Geiers’ paper had failed to disclose, wait for it, their own conflicts of interest on this topic, chief among them that some of the paper’s authors were involved in litigation related to vaccines and autism. Indeed, the Geiers were picked as expert witnesses in hundreds of vaccine-related lawsuits, though many judges dismissed the pair for being unqualified. But the most salient of these breaches of ethics may be what the two did in late 2003, early 2004. They had received ethics approval to go to the Centers for Disease Control (CDC) and access information from their Vaccine Safety Datalink, which collects data on vaccination and health outcomes. On their first visit, they tried to perform analyses of the data that had not been approved for their research project. On their second visit, they attempted to merge data files to create more complete medical records, thus increasing the risk of a breach of confidentiality, and they renamed files for removal which were not allowed to be removed. Conspiracy theorists will claim the CDC was trying to keep information secret; clinical researchers, however, know that large datasets filled with identifiable information should only be used by researchers according to strict rules. Imagine a scientist going through your own medical records willy-nilly and unsupervised, violating their own ethics-approved protocol because they’re on a mission to document something that doesn’t exist. Now imagine David Geier being given access to an even larger dataset and receiving permission by the anti-vaxxer-in-chief to find a connection between autism and vaccines. That’s what’s on the horizon. Dr. David Gorski, an oncologist who has devotedly tracked the modern anti-vaccine movement over the decades, calls the motivated trawling of large health databases by anti-vaccine activists “dumpster diving.” This activity is now mandated by the U.S. government. The Geiers’ dumpster diving at the CDC, however, is just the tip of a disturbing iceberg. I haven’t even mentioned the chemical castration of autistic children. The testosterone-mercury hypothesis The Institute of Chronic Illnesses has its own institutional review board tasked with evaluating and approving or denying research projects involving human participants. In 2007, this board was denounced as consisting of David Geier; Mark Geier, his wife, and two of his business associates; and the mother of an autistic child who was a patient and research participant of Mark Geier’s, and the mother of another child with autism who was a plaintiff in three pending vaccine-injury claims. It should go without saying that the scientist submitting a research proposal to an ethics committee and his buddies should not sit on said committee. It turns the process into a farce. This denunciation was provoked by a paper the Geiers were in the process of having published and which detailed what they had been up to. It turns out that they believed that autism was caused by the mercury in vaccines, and that testosterone could somehow bind to mercury and make it harder to get rid of, creating so-called “testosterone sheets” inside the body. The Geiers were thus injecting autistic children with high doses of Lupron® (also known as leuprorelin and leuprolide), which delays puberty, and then performing chelation therapy on them, where a substance is used to bind to toxins and help the body eliminate them. None of this is supported by good scientific evidence; this is dangerous pseudoscience in the service of an anti-vaccine ideology. Pseudoscience has a patina of legitimacy, and sure enough the Geiers were running actual medical tests on their patients. Per an investigation by the Chicago Tribune, it was revealed that the Geiers would order over 50 different tests, totalling up to $12,000. If one of the testosterone-related tests revealed a value outside of the reference range, Lupron injections would be considered at a daily dose “10 times the amount American doctors use to treat precocious puberty.” Keep in mind that the more medical tests you run, the higher the odds that one of them will turn up something outside the normal range by chance alone. Tests aren’t perfect and “normal” is not always easy to define. Eventually, the Geiers’ aberrant behaviour led to penalties. Dr. Mark Geier’s medical licenses were suspended from every state in which he had one, and his son was charged in Maryland with practicing medicine without a license and fined $10,000. While David Geier is clearly not qualified to be running a study for the U.S. government on the subject of vaccines, he is the ideal candidate for a regime that is institutionalizing pseudoscience within its borders. Doubt is our product The very media outlet that broke the story of David Geier’s latest commission referred to him as a “vaccine skeptic.” Legacy media outlets are failing to meet the moment here, either because of fear of lawsuits or as a misguided attempt to appear neutral. RFK Jr received a similar sanewashing in the media. If we can’t call anti-vaxxers “anti-vaxxers,” we will be unprepared for the outcome of their crusade. The pieces of the puzzle are there for anyone to see. Agencies within the Department of Health and Human Services—like the FDA and the CDC—are being gutted as you read these lines. The FDA’s former commissioner said of his agency that “it is finished.” Dr. Peter Marks, the FDA’s top vaccine regulator, was apparently forced out a few days ago, writing that Kennedy wanted “subservient confirmation of his misinformation and lies.” Meanwhile, a fake CDC website (RealCDC.org) with clear ties to Kennedy’s anti-vaccine organization mixed good science with vaccine misinformation before it was exposed and shut down. This is straight out of the Merchants of Doubt playbook: “doubt,” as one tobacco executive wrote decades ago, “is our product.” You don’t need to forcefully convince people that smoking is healthy; just make them doubt that we really know it’s harmful. The opposite can be done for vaccines. Kennedy has announced a consolidation of divisions within his department and the creation of an Administration for a Healthy America, an Orwellian banner which echoes his “Make America Healthy Again” movement, itself a cargo cult fuelled by pseudoscience. Even more troubling is his desire to establish a vaccine injury agency within the CDC. Currently, people who think they have been injured by a mandated vaccine in the U.S. can receive compensation from the federal government. This was a way to ensure vaccines would continue to be available in the country after a wave of lawsuits in the 1980s. But will this system be maintained? Kennedy’s institutionalization of anti-vaccine pseudoscience—meaning not just making the fringe mainstream but sanctioned by the government—could have a drastic impact on vaccine availability. Geier’s study, born out of the square one fallacy where something well established is argued to be unknown, will assuredly show a link between vaccines and autism through bad research practices. This government-commissioned study will then be used to encourage lawsuits against vaccine manufacturers—from which RFK Jr himself could financially benefit—and here is where we arrive at the final piece of the puzzle. Right now, vaccine makers benefit from the federal no-fault system compensating people believed to have been injured by a vaccine (whether they can successfully prove it or not). This protection could be eliminated. We could subsequently see vaccine manufacturers decide to stop making vaccines for the American market because the risk of unwarranted lawsuits would be too high. The so-called free market would effectively eliminate vaccines in the United States. This is ultimately what Kennedy wants. He has, on multiple occasions, called childhood vaccines “a holocaust,” and he wants to save America from this perceived cataclysm. The outcome of this renunciation of reality will be death and disability, and with international travel, there will be spillover. What can we do in the face of this? As science communicator and immunologist Andrea Love wrote in her newsletter, Americans can call members of Congress, vote responsibly, and support unsanitized public health journalism. All of us, Americans or not, will need to rely on uncorrupted sources of public health information moving forward. American government websites have been captured by science deniers. We need to turn to Canadian, British, European, and international websites instead. Even PubMed, the search engine of the biomedical literature, sits under the NIH and may not be spared from the U.S. ideological purge; I recommend the bookmarking of Europe PMC and OpenAlex as alternatives. In a move that echoes Isaac Asimov’s Foundation, U.S. government websites before Trump returned to office are being preserved and made accessible to the public, through portals such as the Health Data Preservation Project, the CDC Restored, the Data Rescue Project, and the CDC.gov Archive Index. The future looks bleak but to quote a famous fictional scientist, “Life finds a way.” So will science. Take-home message: - David Geier, who has neither a medical degree nor a graduate degree, has been hired by the U.S. government to do a study on whether vaccines cause autism, even though mountains of evidence have shown no such connection - Geier and his father, the late Dr. Mark Geier, have a history of unethical research practices, including violating their own research protocol when accessing CDC data, and David Geier was charged with practicing medicine without a license in 2011 - This commissioned study is one more step toward eliminating vaccines from the United States, as RFK Jr has often called childhood vaccines “a holocaust” @jonathanjarry.bsky.social
#news#science#health
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Bích-Mây Nguyễn :verified:

"In recent weeks, academics who focus on improving the health of lesbian, gay, bisexual, transgender and queer Americans have been subjected to waves of grant cancellations from the National Institutes of Health. More than 270 grants totaling at least $125 million of unspent funds have been eliminated, though the true sum is likely much greater, researchers told NBC News."

nbcnews.com/nbc-out/out-news/t

NBC News · Trump administration axes more than $125M in LGBTQ health funding, upending research fieldBy Benjamin Ryan
#healthcare#science#research
Continued thread
Public
petersuber

Update. "Massive, Unarchivable Datasets of Cancer, Covid, and Alzheimer's Research Could Be Lost Forever"
404media.co/nih-archives-repos
(#paywalled)

"Almost two dozen repositories of research and public #health #data supported by the #NIH are marked for “review” under the #Trump administration’s direction, and researchers and archivists say the data is at risk of being lost forever if the repositories go down. “The problem with archiving this data is that we can’t,” Lisa Chinn, Head of Research Data Services at the University of Chicago…Unlike other government datasets or web pages, downloading or otherwise archiving NIH data often requires a Data Use Agreement between a researcher institution and the agency, and those agreements are carefully administered through a disclosure risk review process."

404 Media · Massive, Unarchivable Datasets of Cancer, Covid, and Alzheimer's Research Could Be Lost ForeverDays before Robert F. Kennedy Jr. announced that 10,000 HHS staffers would lose their jobs, a message appeared on NIH research repository sites saying they were "under review."
#Censorship#DefendResearch#Medicine
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